| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38edb70ccfa0f1f7417b76de6015db11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ac6907ace3d81d89755e6faea0c339
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe61de3d997534a74e94ea466a1afb54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec38b0dc38178bd7b5d4ec41e5c7a859
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cb2e28b549d30bdef01843eaac24036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c807e19ea32770556a68ec06d964e3c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N41-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-10 |
| filingDate |
2009-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e33e852ca05d55792f63e4d2251f7a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66b5b479c4736d28c0e13759cab36ceb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_749076a9ac7c2dbb1f369911ff66f2e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1af582f70e076e587effb3266410534b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23bd7772f4158d4fe12e32fd2f2b6f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e27201e27c92972ff8a6757d6b8a1af |
| publicationDate |
2009-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009131906-A1 |
| titleOfInvention |
Cyclobutyl sulfones as notch sparing gamma secretase inhibitors |
| abstract |
The invention encompasses a novel class of cyclobutyl sulfone derivatives which inhibit the processing of APP by the putative γ-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2477963-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2375895-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2375895-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2477963-A4 |
| priorityDate |
2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |