| abstract |
The present invention concerns a screening method for therapeutic agents for fetal neurological disorders caused by exposure to alcohol or nicotine during pregnancy, and more particularly concerns a screening method for therapeutic agents for fetal neurological disorders caused by exposure to alcohol during pregnancy using a candidate material, by confirming any increase in expression of GABA B receptors and protein kinase A-α, in early-development brain cells, as caused by exposure to alcohol or nicotine during pregnancy in the initial development stage, and by confirming that the expression of the protein is reduced by treatment of the cells with the candidate material. |