http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009130342-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cfe299b05a939b60bf894721905e5d4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e38589fab943bb99c0b50ac59ac2b09a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d399600787439de43c80d640c447ce02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c53838af25f476840c8bf709fc0c7a61 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192 |
| filingDate | 2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f827ce0dc66447867511f2dcfd13b634 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3efc976cc59fc6f5e5f94164a24d627e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70a8d9c859b7dac0e6b5cfa4d960cc31 |
| publicationDate | 2009-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2009130342-A1 |
| titleOfInvention | Improved pharmaceutical composition containing ibuprofen and codeine |
| abstract | The invention relates to a novel ibuprofen and codeine formulation in the form of a tablet containing L-leucine as a lubricant at a concentration of 4 - 15%, which prevents the formulation mixture from sticking to the punches or any other components of the compression machine during the compression process. The novel formulation also contains: talc (0.5 - 5%) and silicified microcrystalline cellulose (30 - 80%). The formulation is preferably provided in the form of a core containing the active ingredients and, inter alia , the L-leucine, part of the talc and the silicified microcrystalline cellulose, said core being coated with a composition containing a copolymer of methacrylic acid and ethyl acrylate. The above-mentioned tablets have: no exfoliation problems, sufficient hardness with suitable friability to allow subsequent coating, disintegration values of less than five minutes and dissolution values for both active ingredients in accordance with those required for quick-release tablets. |
| priorityDate | 2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.