| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6a9fa49d3a6f6197f19b2f16158f9085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a563d8b19f0cbe841b9691d2442d0752
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676b80da7ac92b84e447a83fb1630ae1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8031f76cbb078505d3fa947f47dc6447 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2009-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa9949adfdd9df4452fef45f0c5eb9e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17ac73e83636ebb796251d540bf9de3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f2e0f53657eaa28df7bf22286b1611e |
| publicationDate |
2009-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009126563-A1 |
| titleOfInvention |
Methods and compositions for the regulation of microrna processing |
| abstract |
Provided herein are methods and compositions for the regulation of microRNA processing. The invention presents methods for inhibiting the activity of a Lin-28-like polypeptide and methods for treating a subject with cancer comprising administering to a subject with cancer a compound that inhibits the activity of a Lin-28-like polypeptide. Compositions comprise isolated polynucleotides and expression cassettes comprising the same that promote the processing of at least one of a regulated primary microRNA transcript by Drosha and a regulated precursor microRNA by Dicer when introduced into or expressed in a cell. Compositions and methods are also provided for the selective suppression of target polynucleotides by a microRNA based on the level of expression of a Lin-28-like polypeptide within a cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11027023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023283405-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10934542-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2015099122-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10238752-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013125967-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020047234-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10612020-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3088524-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11142769-B2 |
| priorityDate |
2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |