| abstract |
A new composition for treating peri-implantitis, i.e. of bacterial inflammatory processes that occur in a bone tissue close to a dental implant, comprising at least one biocompatible acrylic resin, said or each acrylic resin permeable to water, but insoluble to water; an antibiotic mixture; an organic solvent that in use is adapted to gradually evaporate, such that said at least one resin forms a protective film that gradually releases said antibiotic mixture. The antibiotic mixture comprises piperacillin sodium and tazobactam sodium in a predetermined weight ratio. In particular, said or each acrylic resin is permeable to water, but insoluble to water, and ensures the permanence of the film in the mouth even if saliva is present and at the same time releases piperacillin sodium and tazobactam sodium. The composition achieves a gradual release of the therapeutic agent directly close to the pathogenic process and allows eliminating the bacterial deposits from the raw surface of the dental implant. |