http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009114763-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_165f5145d6645a07a1520167fed24600 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d4cc394361dfb301eb5a99e69c4bc25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e8049defa7ca43e4aec56b5275213b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-924 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate | 2009-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd3ebab9eae3c658c1f2ceef7f4ab424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0453a13a7ba42279b379451730c431b5 |
publicationDate | 2009-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2009114763-A2 |
titleOfInvention | Enzymatic substrates for multiple detection systems |
abstract | An inventive substrate is provided which includes a substrate compound of formula A—B 1 —B 2 —B 3 —B 4 : wherein A is a sugar moiety; B 1 is a linker moiety allowing the conjugation of moiety A and the remaining structure of the substrate; B 2 is a linker moiety with a free reactive amino group so as to be available for reaction with carboxylic acids or detectable tags; B 3 contains a permanently charged element such as a quaternary ammonium group so as to increase sensitivity for mass spectrometry analysis; and B 4 of various carbon length conferring specificity amongst individual substrates in detection methods. Also provided is a molecule of the formula B 1 —B 2 —B 3 —B 4 , with similar structural characteristics to an enzymatic product produced by the action of a target enzyme on an inventive substrate. Further provided are methods for using inventive substrates for detecting enzymatic activity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591544-B2 |
priorityDate | 2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 266.