| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ffdd0403966b3257cdff37810d77910
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e67e846051da40b697d3f9360d82356f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bf2553dd8fa6c90c17903fd7d04845c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6be125d1a2ca30b9999a149a655d02b3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0657
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2009-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5abce810b4c69a096efe248b2d9c26d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93fc88493d3034a1d9a29482305100ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a27b45966acade260cbd4995ef578c74 |
| publicationDate |
2009-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009108772-A1 |
| titleOfInvention |
Cardiac myocyte morphogenic compositions and methods of use therefor |
| abstract |
Disclosed are methods for inducing cardiomyogenic differentiation in cells that are competent for differentiation along the cardiomyogenic lineage such as certain unfractionated bone marrow mononuclear cells (BMMNCs). In some embodiments, the methods include contacting a plurality of unfractionated, density gradient-separated BMMNCs with a cardiomyocyte differentiation- inducing amount of a Wnt11 gene product for a time and under conditions sufficient to induce cardiomyocyte differentiation in at least a subset of the BMMNCs. Also provided are methods for treating an injury to cardiac tissue in a subject using cells that have been induced to differentiate along the cardiomyogenic lineage, recombinant host cells comprising an expression vector that encodes a Wnt11 polypeptide or a functional fragment thereof, and systems for inducing cardiomyogenic differentiation in a cultured cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9151744-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012045770-A1 |
| priorityDate |
2008-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |