| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79a344be5e50af59cff572f666b6db2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c36224c701ea2944aba5819239c15b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13c180dc339db67b964dc1c9bb7971e4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-03016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
| filingDate |
2009-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68aacf611695d7263f036f243947c235
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d0b8c5734654489f1cd4a8960a6af74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd34f71fb97be266155f6c73185c9aa |
| publicationDate |
2009-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009108745-A1 |
| titleOfInvention |
Structure of a protein phosphatase 2a holoenzyme: insights into tau dephosphorylation |
| abstract |
Embodiments of the present invention relate to crystals and atomic coordinates for PP2A, as well as methods for using these atomic coordinates to prepare modulators of PP2A and inhibitors prepared using such methods. Further embodiments relate to biochemical analyses of the interactions of PP2A alone or in complex with Tau. Further embodiments relate to compositions including mimetics and small molecules, optionally, secondary agents, which may be used to treat disorders in which PP2A activity and/or Tau plays a contributing role. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016203118-A1 |
| priorityDate |
2008-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |