Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b26fa2970e120c7de437191e9fee342 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13550a2e931b7820247a58278354ee62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42bd8c170a9381e799c4b58962b138ed |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-60 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
filingDate |
2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e8bdd039cbcafdf096948b8e7234a89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d510c9681154e9aece8c3b659b7c48a |
publicationDate |
2009-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009108364-A2 |
titleOfInvention |
Antagonistic analogues of ghrh |
abstract |
There is provided a novel series of synthetic antagonistic analogues of hGHRH(l- 29)NH 2 (SEQ E) NO: 1). These analogues inhibit the activity of endogenous hGHRH on the pituitary GHRH receptors, and therefore prevent the release of growth hormone. The analogues also inhibit the proliferation of human cancers through a direct effect on the cancer cells. The inhibitory potencies of the new analogues result from replacement of various amino acids. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111533800-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111533800-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021160188-A1 |
priorityDate |
2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |