Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e23a4c9cd982ccdb6082585045b94b7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1eed52535c1bed81a707da41038a3c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3aeb5e606c1fb1a2ff49eb8ab418b01a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24430c627c7e011dc7560cb085ee51b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28627059e1e1bdd2890ef9b952b82b8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e559743173473475142b7bd8a978298 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4365 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 |
filingDate |
2009-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f35216b554f717e9f359a3800dd9ba61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d1e2ab1d6fd202e2963023ae358deeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d3b9bbb820faae7ced45694394369a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75426c2ada8bdb2f83cd0e4fd6bf72dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4740aa4d231288aeb95d3043b9223d94 |
publicationDate |
2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009104932-A2 |
titleOfInvention |
Composite preparation |
abstract |
The present invention provides a composite preparation which comprises: a prior-release section comprising aspirin or a pharmaceutically acceptable salt thereof as a pharmacologically active component; and a delayed-release section comprising clopidogrel, an isomer thereof or a pharmaceutically acceptable salt thereof as a pharmacologically active component. The composite preparation of the present invention exhibits a far better effect in preventing platelet aggregation than does simultaneous oral therapy or treatment with the respective single preparations, and not only can it improve the patient's drug-taking compliance by administration once a day but it can also reduce the adverse reactions which follow long-term administration of aspirin. The composite preparation of the present invention is also advantageous in that it exhibits an outstanding effect in inhibiting blood platelet aggregation despite a reduction in the amount of aspirin ingested, and in that it converts clopidogrel resistance into susceptibility and prevents serious adverse reactions caused by clopidogrel resistance and in that it can be stored over the longer term since it is stable under common storage conditions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013507400-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109180701-A |
priorityDate |
2008-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |