abstract |
The disclosure provides combinations of antibodies and functional fragments, and methods of using antibodies and functional fragments in combination (e.g. each antibody administered individually to a subject sequentially or administered to a subject as a combination composition). Antibodies include IgMs and IgGs. IgMs include combinations of IgMs (e.g., two or more IgMs). IgGs include combinations of IgGs (e.g., two or more IgGs). Combinations include combinations of IgMs (e.g., two or more IgMs), combinations of IgGs (e.g., two or more IgGs) and combinations of IgM and IgG. Methods include administering combinations of IgMs (e.g., two or more IgMs), combinations of IgGs (e.g., two or more IgGs) and combinations of IgM and IgG to a subject. |