abstract |
The purpose of this object is to provide an oral cavity disintegrating tablet which quickly disintegrates in the oral cavity, can be easily produced, has a desired appropriate hardness and is excellent in storage stability, and a method of producing the same. An oral cavity disintegrating tablet which contains (a) one or more sugars or sugar alcohols selected from the group consisting of mannitol, lactose, xylitol, sucrose, erythritol and glucose and (b) a hydroxypropyl cellulose having a low substitution degree and is produced by a process comprising the steps of granulating a composition containing the components (a) and (b) as described above by the agitation granulation method and then compression-molding the granular product thus obtained, wherein the oral cavity disintegrating tablet is substantially free from a starch-based disintegrating agent. A method of producing an oral cavity disintegrating tablet which is substantially free from a starch-based disintegrating agent, comprising the steps of granulating a composition containing the components as described above by agitating and then compression-molding the granular product thus obtained. |