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filingDate 2008-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2009-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2009079922-A1
titleOfInvention Humanized anti-cd34 monoclonal antibody, the preparation and uses thereof
abstract Provided are a humanized anti-CD34 monoclonal antibody and the preparation thereof. The humanized anti-CD34 monoclonal antibody keeps the affinity and specificity of its original murine monoclonal antibody. The antibody can be conjugated with magnetic nano material to make immunomagnetic beads to screen marrow hemopoietic stem cells. It can effectively reduce the incidence rate of HAMA and improve the security of clinical transplantation of hemopoietic stem cells and can be used in treatment of some malignant hematologic diseases and solid turmors.
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