| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe930ce22cc01d7bd40ca292a12bf6e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ba4bce35fe3448d25cdc81e438e0f9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb351a5a4e03ee3773bd0df5dbae9ac3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-757
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-75 |
| filingDate |
2007-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd8536823b07cd389106214858c6e9ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17b16029d6ab145c13a9191b751b416e |
| publicationDate |
2009-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009079876-A1 |
| titleOfInvention |
3-acylated shikimic acid or methyl (ethyl) shikimate |
| abstract |
Disclosed is the 3-acylated shikimic acid or methyl (ethyl) shikimate derivatives. Shikimic acid is a kind of natural product having physiological activity and has effects on thrombus and alleviating brain damage caused by focal cerebral ischemia. However, it cannot be absorbed easily with high polarity, and thus it is important to produce the monoacylated derivatives, improve the polarity, and enhance the fat solubility and the ability of crossing the blood-brain barrier. 3-acylated shikimic acid or methyl (ethyl) shikimate derivatives will be a kind of compounds having unique physiological activity and may be developed into a new class of pharmaceuticals; meanwhile, 3-acylated shikimic acid or methyl (ethyl) shikimate derivatives keep the three chiral centers of the shikimic acid perfectly in structure, and thus they can be useful starting materials and intermediates for synthesizing chiral pharmaceuticals. |
| priorityDate |
2007-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |