Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6403426a2fbec30b4e81562537ca40b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_515f30a233965a7b099d9ffa4d433402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9ab5d8af1c568987290d88ccdbe1010 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6a156dc3b786dd2886c7a1908f70286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b2b250d3f776665fc10408a3fc94c37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9737a80aa299f37fe899ecb1e3af3202 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2008-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_919064eeab0d49b6e248130e4938dd16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ece6c864ed4dc6e323acf442a56c89c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fcadebb1fa951a4a3d9cb34048b4b4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb0eeb322baaa9129feb82e0e5d111a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bb4e69d84c2dea3b74eda43d2e14b28 |
publicationDate |
2009-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009070211-A1 |
titleOfInvention |
Sustained release of apo a-i mimetic peptides and methods of producing them |
abstract |
A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the particular region or a perivascular site, wherein the peptide has a property that renders the peptide effective in reverse cholesterol transport. A composition including an apolipoprotein A-I (apo A-I) synthetic peptide, or combination of an apo A-I synthetic mimetic peptide and an Acyl CoA cholesterol: acyltransferase (ACAT) inhibitor in a form suitable for delivery into a blood vessel, the peptide including an amino acid sequence in an order reverse to an order of various apo A-I mimetic peptides, or endogenous apo A-I analogs, or a chimera of helix 1 and helix 9 of endogenous apo A-I. |
priorityDate |
2007-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |