Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f31aad9121371d74a12cbc13235cc5ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4239783a50609f52e7c767e426db33bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate |
2008-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8e04d8b68c85b9a3a629bb57132c2b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee761d11fdc2f67f821ef678c3a91df5 |
publicationDate |
2009-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009067182-A2 |
titleOfInvention |
Phospholipid compositions and uses thereof |
abstract |
We have discovered that phospholipids diundecanoyl (C1 1:0-C1 1:0) and dilauroyl (C12:0-C12:0) phosphatidylcholine (PC) act as agonists of the LRH-1 receptor. We have also shown that administration of these lipids to diabetic mice reduces blood glucose levels. On the basis of these discoveries, the present invention features compositions that include these lipids and structurally related lipids. Also featured are methods of treating metabolic disorders and inflammatory bowel disease, lowering blood glucose levels, and increasing LRH-1 receptor activity in a subject by administration of these lipids. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011144725-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10765688-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013210143-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9512407-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229634-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2598125-A2 |
priorityDate |
2007-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |