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filingDate 2008-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bd6dc875b89b645536b9aaf4a7c332b
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publicationDate 2009-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2009055937-A1
titleOfInvention Altered n-cadherin processing in tumor cells by furln and proproteln convertase 5a (pc5a)
abstract The present invention relates to a method for diagnosis and/or prognosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a subject by determining the molecular form of cadherin at the cell surface of cancer cells in the subject. The invention also relates to a method for preventing, inhibiting or treating cancer or its metastasis in a subject by increasing the adhesive forms of cadherin and/or decreasing the non-adhesive forms of cadherin at the cell surface. The invention also relates to a method step of determining the expression level of furin and proprotein convertase 5A (PC5A).
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