abstract |
The present invention relates to diarylhydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.wherein R3 is selected from the group consisting of hydrogen, cyano, formyl, wherein R1 and R2 together comprise eight or fewer carbon atoms and are, selected from the group consisting of alkyl substituted alkyl and, together with the carbon to with they are linked, a cycloalkyI or substituted cycloalkyl group, |