| abstract |
Disclosed is a pharmaceutical composition which comprises cetirizine or a salt thereof as an pharmacologically active ingredient and which has both of a rapidly disintegrating property and a sufficient hardness. Specifically disclosed is a pharmaceutical composition comprising (i) cetirizine or a salt thereof, (ii) a cyclodextrin, (iii) a corn starch, and (iv) a cellulose. It is found that the pharmaceutical composition has both of a property of disintegrating rapidly in an oral cavity and a sufficient hardness for withstanding usual production processes, distribution and usage thereof, and can mask a bitter taste derived from cetirizine or the salt thereof. |