| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_115c4dec4bde5bfab8c813c0aa1ac5cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8432ebff5a06ee8a6ffec8cc7611fbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e84cb6002fb18499ac6c633d535b9f72 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate |
2008-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5acb3859a51c39e86e6444d866a06e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64bda1fbbe85d1b2788d8c7ce52c796 |
| publicationDate |
2009-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009054004-A3 |
| titleOfInvention |
Process for the preparation of sorafenib |
| abstract |
A novel and improved process for the preparation of sorafenib (4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide) of formula (I) involving a novel intermediate of formula (II) as key intermediate is disclosed. Sorafenib tosylate, available in the market as Nexavar is a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinase that promote angiogenesis. |
| priorityDate |
2007-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |