| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_891bdec36f1b03492ff2af6885482c6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9043ee094fc4d3f918edf52186ddd8d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbf0881c2ac934bdb32c58a7a5692088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f09c6fa4067641fe669c0d21b94c2830
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6060eac6129a4c87d0ad1930d64ef067 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01146 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2008-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1a036695c6c84ba5782bff472f99ee5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6e00571cbe4475ac21ca586cefff169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e48bb081f0e32f59dfa22dc7faa3d039
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_906e6a76a4ce8534cfd67a78e3582809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edcfaf71df271422e18efd69d5c19123 |
| publicationDate |
2009-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009048903-A1 |
| titleOfInvention |
11 beta hydroxysteroid dehydrogenase type 1 |
| abstract |
The invention provides gene-targeted non-human animals comprising a genetically modified 11βHSD1 gene encodes a mutant 11βHSD1 polypeptide which is modulated by human 11βHSD1 modulating compounds. The invention further provides cells expressing mutant 11 βHSD1 and cells isolated from gene-targeted animals, which cells produce a mutant 11βHSD1. The invention further provides methods of identifying agents that modulate 11βHSD1 activity, and are useful to treat 11βHSD1 -related metabolic disorders. |
| priorityDate |
2007-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |