abstract |
An isolated Tat peptide as anti-HIV vaccine, said peptide consisting of 11 to 15 consecutive amino acids of Tat 41-55 comprising at least positions 44 to 50, said Tat peptide binding to at least three of the most prevalent HLA-DR molecules in the Caucasian population and consisting essentially of an immunoprevalent T CD4+ cell epitope in humans. |