Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a16bf57d74a279ab87e74790ead4e655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fa298ae68277e6cb4a66851d21d137e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e8f6dfda7e4d3177b4e661df8bd0dd0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-001 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 |
filingDate |
2008-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76a4e202dfea80bc5f0bece7daf34600 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccd53a78eecb509cbab6a619d7af82a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71a93378f90d3c6402a840b0c85a238f |
publicationDate |
2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009039185-A1 |
titleOfInvention |
Uses of immunologically modified scaffold for tissue prevascularization and cell transplantation |
abstract |
This invention provides method of making and using of a porous 3 dimensional cyclic RGD peptide-modified alginate scaffold that can be loaded with different cell types and/or growth factors for implantation at sites of tissue damage to promote tissue regeneration. The cyclic RGD peptide promotes vascular formation of the host tissue, cell binding and survival of seeded cells. In vitro, cyclic RGD peptide promotes cell survival more efficiently than linear RGD peptide, which results in improved live cell numbers after prolonged culture. Scaffolds with growth factors but without cells can be implanted to create a vascular bed in which cells are transplanted at a later time point, for example pancreatic islets. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019106685-A1 |
priorityDate |
2007-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |