Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b00934009cfcc656fe8fd3fbb5c1965a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D59-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D59-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-00 |
filingDate |
2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25e97ffa87fe9e6707502eed92160e90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_139112970ea6e86979e3e6a7e5d95878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f5232cdb2d845ca4103b4241b85683 |
publicationDate |
2009-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009036193-A1 |
titleOfInvention |
Identification of proteins in human serum indicative of pathologies of human lung tissues |
abstract |
A method of identifying proteins present in human serum which are differentially expressed between normal individuals and patients known to have non-small cell lung cancers and asthma, as diagnosed by a physician. Human serum specimens from each population are digested with trypsin or any other suitable endoproteinase and analyzed using a liquid chromatography electrospray ionization mass spectrometer. Mass spectral data from each population is compared to determine proteins with expression intensities which are significantly differentially expressed between the normal, asthma, and lung cancer populations. Eleven proteins are found to have expression intensities which are significantly differentially expressed between the populations. Finally, the identity of the eleven proteins are obtained by comparing the mass spectral data with known databases having libraries of mass spectral data of known proteins. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10620184-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106596977-A |
priorityDate |
2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |