http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009030650-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd9a62352aaf92a9c55d2e144ed29378 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df0d46951ab05b1644baf7f0292e2dd3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b013972096cb829c50a031edc741396d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 2008-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_662e32578d2a9d5547b164da1f07bc5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9833224737d8fd07fa0e55881ca208a4 |
| publicationDate | 2009-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2009030650-A1 |
| titleOfInvention | Inflammation-induced anti-inflammatory gene expression |
| abstract | According to one embodiment of the present invention, a self regulating DNA non-viral expression vector is provided that allows after non-viral ex vivo gene therapy for the controlled and regulable inflammation-specific expression of anti-inflammatory polypeptide gene products in the recipient's joint tissues. The inventive gene expression construct comprises a RNA polymerase promoter sequence that is induced by inflammation and which is operable in a mammalian cell, a transcribed sequence under the control of said promoter sequence, encoding a transcription product that has the ability to modulate the inflammatory response, and/or encoding the mRNA for a polypeptide gene product that has the ability to modulate the inflammatory response, whereby the inflammatory response is modulated by a negative feed back response of said gene product on said promoter sequence. |
| priorityDate | 2007-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 381.