| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd110ed61f4b7abacf10f61321e2a0f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc365d0d4cf537a503859144cd924ad6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0699ffc64cdc83da45fffa9ac1df8e11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8302ff135b7d5a2846e701ba0a51c70 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7233 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| filingDate |
2008-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2e27333a366566db6412361f0a60386
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01b8893140fd4a29d038d8596a426116
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0feb80e1421e492f36e30e72785d29e7 |
| publicationDate |
2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009029231-A2 |
| titleOfInvention |
Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry |
| abstract |
Liquid chromatography-mass spectrometry to verify the presence or absence of the extractables introduced into a biopharmaceutical product during manufacture, filtration or storage at above a certain concentration. The method disclosed herein can be used to detect the presence of extractables in the actual biopharmaceutical product rather than a surrogate solvent system. Detection of the extractables in the actual drug product provides an accurate description of the leachables profile likely to be introduced to the human or animal patient. In one embodiment, the extractable are introduced by filtration of the biopharmaceutical product. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113899837-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10912864-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103293253-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103293253-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8436297-B2 |
| priorityDate |
2007-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |