http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009028880-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef11443544f9d2e97b0fdec2f082e15e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59818dea1fc6bb7398c0979d0ceebc49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f533c9f87584e3a8376ef45df72d2463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3ea5b0728404f4008cc1235c2f3ee64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc22a92a5fa704dfd5069e3eb129defb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad0bdf08a13b61cc01b92e6f011f2f61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4e251aad9cd01bf9a53e871f356ddba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fb2b4469d448e1b297febd9c4cf4dc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed8302f4dc14ee367226867a2a6d9633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a56f523e37652b3352e424ac8c97a258 |
| publicationDate | 2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2009028880-A2 |
| titleOfInvention | Biomarker composition for detecting diabetic retinopathy and diagnostic kit therefor |
| abstract | The present invention provides a biomarker composition for detecting diabetic retinopathy comprising at least one protein selected from the group consisting of proteins as set forth in SBQ ID NOS: 1 to 169. And also, the present invention provides a kit for diagnosing diabetic retinopathy, comprising a molecule specifically binding to at least one protein selected from the group consisting of proteins as set forth in SBQ ID NOS: 1 to 169. It has been newly found that 105 proteins as set forth in SBQ ID NOS: 1 to 105 are significantly over-expressed in the vitreous humors obtained from PDR patients, while 64 proteins as set forth in SBQ ID NOS: 106 to 169 are significantly over-expressed in those obtained from normal people. Therefore, the proteins can be used for biomarker capable of detecting diabetic retinopathy.The biomarker can provide fundamental information in researching vitreoretinal disorders, such as diabetic retinopathy. Especially, the newly found proteins may be applied to a kit for diagnosing diabetic retinopathy with a molecule specifically binding thereto, e.g., a monoclonal antibody. And also, it has been newly found that the levels of thyroxine-binding globulin precursor (TBG) in both vitreous and plasma of PDR and NPDR states and in plasma of diabetes mellitus state, are outstandingly higher than in non-diabetic control (MH or normal control). Therefore, TBG may be applied to a diabetes mellitus biomarker, and a kit for diagnosing diabetes mellitus with a molecule specifically binding thereto. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8497076-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015514227-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8609612-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8497077-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8168396-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8530175-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10408847-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011100197-A1 |
| priorityDate | 2007-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.