| abstract |
A compound represented by the general formula (I), a salt of the compound, or a hydrate of either thereof. They have an excellent antipruritic effect and have an excellent metabolic effect. The compound represented by the general formula (I), salt of the compound, or hydrate of either thereof, in a preparation for external use, has excellent absorbability into the skin. The preparation for external use has excellent stability because the ingredients incorporated are less apt to separate out even in long-term storage. (I) [In the formula, R represents hydroxy, C1-6 alkoxy optionally substituted by C1-6 alkoxy, or amino optionally substituted by C1-6 alkyl.] |