Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45a3703d03a4b21be619937f5ad63b8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_462325f221dcfe3742675fadc2eaaaa9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16134 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-21 |
filingDate |
2008-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b42be57477d264b409ba21eae123030 |
publicationDate |
2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009021230-A1 |
titleOfInvention |
Hiv-1 gp41 neutralization domain and use thereof |
abstract |
The invention relates to a region of the HIV-I gp41 protein that contains, at least in part, an epitope that allows potent neutralization of resistant virus particles. This site is present in the C-terminal heptad repeat region of gp41 (HR2), and adjacent to, but distinct from the MPER. Vaccines containing this region as well as monoclonal antibodies which specifically bind to this region and neutralize an HIV-I primary isolate are also provided as is a method for stimulating the formation of antibodies that neutralize infection by an HIV isolate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021185851-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2410733-R1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2447277-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012055985-A1 |
priorityDate |
2007-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |