| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d91821e0c61101e32321a9a94918ba1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d229687f0e02f1a09038e165f28be97f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f698690af46a7a1a6635e249ef7db265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98abe1ffaaa5be6fa6756dd061f1ddfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c05da519756b6b8603fff2255ba4c46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdd8bf746673cb795a19d12da2a2008d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef96befd6ecad010d07633623e9adc2a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2541-101 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2008-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2aaebf7705a5b49fc6602c29844c3a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4940e84c0375c26c1147f829304c6092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_890117f7d0ba6d07a7e2f704562f7628
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_596aa5fe5b080fef81fb3abdd891026e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99dd2d2fd8b094b138bfa00c735d0529
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2170330040b239d07b25ddb934b5f5e |
| publicationDate |
2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009012410-A1 |
| titleOfInvention |
Improved selex and photoselex |
| abstract |
The present disclosure describes improved SELEX methods for generating nucleic acid ligands that are capable of binding to target molecules and improved photoSELEX methods for generating photoreactive nucleic acid ligands that are capable of both binding and covalently crosslinking to target molecules. The disclosure further describes nucleic acid libraries having expanded physical and chemical properties and their use in SELEX and photoSELEX; methods for increasing the crosslinking efficiencies of photoaptamers; methods for producing photoaptamers having selective modifications that enhance functionality and minimize non-specific photoreactions; and methods for generating truncated nucleic acid ligands from nucleic acid ligands of longer length. The disclosure further describes aptamers and photoaptamers obtained by using any of the foregoing. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926566-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016050850-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3049523-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9994857-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10927380-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018005974-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10422794-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10648972-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10316321-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9090896-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3693472-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208663-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10392621-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3044334-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2013099762-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013099762-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016531593-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10221421-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105555957-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014068408-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017149097-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11111495-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015049356-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2019208237-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11578330-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544419-B2 |
| priorityDate |
2007-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |