| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7339013f8d65342d0c9dae36c6a568a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_130aa3d7cce06e52e8149811f4985ed7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f7b665fb8f15d0e2b0911539d39f8a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abf4e7e4fcb230f13c2a0fde8cc6faee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9b7a45a52b696d62858f6794b1acd79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a80b0e53662e07dd8df6a6b5f14aa512 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-267
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-273
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-273
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-20 |
| filingDate |
2008-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c4a6dc9fac5e508cf54c549a7436dae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e9b8e876643a065a0f06fcd2e3faef7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f35fd4d1e2e7af641048175b552b7cbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7fb466af4e0f956ca6c89c44db15c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2081355bd243327e8a86f163605d9b8f |
| publicationDate |
2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009010554-A1 |
| titleOfInvention |
Process for the enantioselective preparation of pregabalin |
| abstract |
The invention provides a new enantioselective process for the preparation of (S) -pregabalin, or a pharmaceutical acceptable addition acid salt comprising: acid hydrolysis of the dioxolan ring of a chiral compound of general formula (I) to obtain compound of general formula (II); oxidation of compound (II) to obtain a compound of general formula (III) and transforming compound (III) into compound of general formula (IV); subjecting compound (IV) to basic hydrolysis to obtain a compound of general formula (V) which is reduced to obtain enantiomerically pure S-pregabalin. The invention also provides new chiral intermediates involved in the process. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7763749-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7586005-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8212071-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8097754-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7923575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7619112-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7851651-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7973196-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7678938-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960583-B2 |
| priorityDate |
2007-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |