abstract |
Compounds of Formula (I) or (II), and methods of making and using thereof, are described herein. wherein M represents a macrolide subunit, n is a C1-6 group, optionally containing one or more heteroatoms, wherein the carbon atoms and/or heteroatoms are in a linear and/or cyclic arrangement, D is an alkyl or aryl group, A is a linking group connected to D, B is an alkyl, wherein M represents a macrolide subunit, R1, R2 and R4 are independently are selected from hydrogen, a C 1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, a C1-6 alkanoate group, a C2-6 carbamate group, a C2-6 carbonate group, a C2-6 carbamate group, or a C2-6 thiocarbamate group, R3 is hydrogen or -OR5, R5 is selected from a group consisting of Hydrogen, a C1-6 alkyl hgroup, a C2-6 alkenyl group, a C2-6 alkynyl group, C1-6 alkanoate group, C2-6 carbamate group, C2-6 carbonate group, C2-6 carbamate group, or C2-6 thiocarbamate group. |