| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f53e232b008d257bf87f62bce95281fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2c99ad962aab260a349acc51e23c44c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5715ab06de4672167063959fb28baffb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C259-06 |
| filingDate |
2008-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2239cbc669044c26726866c226b3e05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2219bc3202f06fd851c30f2b6703a5a9 |
| publicationDate |
2008-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008154905-A2 |
| titleOfInvention |
Modifications of the histone deacetylase inhibitor suberoylanilide hydroxamic acid |
| abstract |
The application relates to compounds of general formula (I) Ar-[CH2]m-Z1-N(Z2-R2)-Z3-[C(O)]r-[CH2]n-Y1-[C(O)]s-Y2-R1, in which the variables can take the values specified in the application. In particularly preferred individual compounds of formula (I), -Z1-N(Z2-R2)-Z3-[C(O)]r- forms an -O-NH-C(O)- or -NH-O-C(O)- group. Said compounds (I) are suitable as medicaments for the treatment of cancer diseases. The effect thereof is due to histone deacetylase inhibition. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107522654-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107522654-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102009019852-A1 |
| priorityDate |
2007-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |