| abstract |
The present invention provides compositions and methods for use of siRNA mixtures with appropriate delivery systems to treat various ocular diseases. The invention includes compositions of siRNA targeted sequences, siRNA duplexes, and siRNA mixtures to inhibit expression of genes causing ocular disease, either from infectious virus or arising spontaneously in the patient. Further, the compositions include carrier polymers for siRNA agents that deliver the agents to eye for effective therapeutic treatment. |