Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af463d4e837e20fef0fd79ae5ecaa01e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5d97ee92861fde80cd1d7c9cf2ddf84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6e4a54a61ccf2f9cb4d46d5160eafe6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-765 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-765 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a01b53f24e6d743c0fcb6e443ab94ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_214b14298970648151f3bd596898e5ba |
publicationDate |
2008-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008143494-A1 |
titleOfInvention |
Assay for detection of prostate cancer by means of proteolytic hsa markers |
abstract |
The present invention relates to a new assay for prostate cancer and peptide markers useful in said assay. It has been found that the serum of prostate cancer patients with metastasis comprises a different set of proteases and proteolytic enzymes than healthy controls. This results in different degradation products of human serum albumin (HSA), which can function as markers for assaying the presence of prostate cancer. Further, the proteolytic characteristics of the serum can be tested by applying a synthetic peptide to the serum and assaying for its degradation products. Specific proteolytic markers are peptides comprising the HSA fragments HPDYSWLL or HPYFYAPEL. |
priorityDate |
2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |