| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_220b5f930cc6f61edfe7739814067f01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d48685c5fffe9de942228601e5f37a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b0e4d5fe911a7499eea7486068d7ebc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2720-12022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2720-12021 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-13 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-14 |
| filingDate |
2008-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be58efb0c60ea272c21233c042cee37c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f0ab1ec7b87ffd237be544f8f889f0 |
| publicationDate |
2008-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008141448-A1 |
| titleOfInvention |
Mutant reoviruses and methods of making and using |
| abstract |
The present invention provides for a mutant reovirus and a genetically-engineered ISVP. Specifically, the present invention provides a mutant reovirus that lacks or exhibits a reduced expression of the sigma3 polypeptide or that lacks a functional sigma3 polypeptide. The mutant reovirus described therein can be used to generate and stably propagate ISVP. Compositions including the mutant reovirus and methods of using such mutant reovirus are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009050573-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11077157-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009050573-A3 |
| priorityDate |
2007-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |