| abstract |
A microscale solution for conducting [18F] fluoride phase transfer and subsequent radiosysnthesis of 2- [18F] FDG that eliminates the azeotropic drying process. [18F] fluoride phase transfer is performed using an inexpensive disposable microchip (310). Additionally, each subsequent each step may be performed on the same single microchip (310). The integrated microchip (310) provides a microchannel (312) having a first resin chamber, or reservoir, (314) for 18F transfer, a labelling reactor (316), a deprotection reactor (318), and a second resin chamber, or reservoir, (320) for purification. |