http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008137228-A1

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filingDate 2008-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2008-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008137228-A1
titleOfInvention System and method for local field stimulation
abstract A system is provided for stimulating one or more cells, wherein the stimulation is sub-threshold and may alter a transmembrane potential of the one or more cells. For some populations of cells it may be possible to affect the transmembrane potential to gain a therapeutic benefit. Cells of the sino-atrial node spontaneously depolarize predominantly due to the slow depolarization of transmembrane potential. The present system may provide sino-atrial cells with a local field stimulation that while not eliciting an action potential may nonetheless alter local transmembrane potential. Such alteration of transmembrane potential may permit an increase or decrease in a rate of depolarization, and hence modify heart rate.
priorityDate 2007-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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