| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f166d5dbcbb9fcb0a24ad6c7a68c534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7961d6a6c5ffd1571d3911e9272b2151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ef10ba5158fbdcc895e3a610eec9e90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdaeb29bff8e94aec1d667ec58dc6761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f363f065ab475124872ec9bae4242a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aeeae3a1e9c2f6b4db133adad89691b1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
| filingDate |
2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abbb4c48c423060cc6d9d09626ec7c0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b79b649dd79a67886d9c6b9e203e3037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9e59a6385cab744eb743b7771d501d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_217024619cdcd43807af664aeb2479f0 |
| publicationDate |
2008-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008128050-A2 |
| titleOfInvention |
Methods for identification of modulators of carm1 methyl transferase activity |
| abstract |
This invention relates to CARM1, CARM1 binding pockets, or CARM1-like binding pockets. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to CARM1 protein, complexes of CARM1 protein, homologs thereof, or CARM1-like protein or protein complexes. The invention also relates to crystallizable compositions and crystals comprising a CARM1 protein or homologs thereof. The invention also relates to methods of identifying binders of CARM1 proteins. The invention also relates to methods for determining the intracellular activity of CARM1 methyltransferase and methods for identifying an agent that inhibits the intracellular activity of CARM1 methyltransferase. |
| priorityDate |
2007-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |