http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008124931-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b628ab81e049bcc77a733f92cb051c2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd38b7007d8437dbc1e38a6c029b7b49 |
| publicationDate | 2008-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008124931-A1 |
| titleOfInvention | Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis |
| abstract | The present invention relates to methods for modulating, disrupting or enhancing the clearance of copper/zinc superoxide dismutase 1(SOD1) aggregates in astrocytes or motor neurons in a subject, by administering a medicament comprising a therapeutically effective amount of a cyclohexanehexol derivative. In another aspect, the invention provides a medicament comprising at least one cyclohexanehexol derivative of formula III or IV useful in preventing or treating amyothropic lateral sclerosis (ALS), improving motor neuron function and slowing the degeneration or death of motor neurons in brain stem, spinal cord or motor cortex. These medicaments may be administered orally, intravenously, intraperitoneal, subcutaneous, intramuscular, intranasal or transdermal. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833420-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859628-B2 |
| priorityDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1011.