http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008124930-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b628ab81e049bcc77a733f92cb051c2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-047 |
| filingDate | 2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd38b7007d8437dbc1e38a6c029b7b49 |
| publicationDate | 2008-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008124930-A1 |
| titleOfInvention | Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases |
| abstract | The present invention relates to methods to modulate the assembly, folding, accumulation, rate of aggregation, oligomerization or clearance of proteins or fragments comprising PoIyQ, by using compositions comprising cyclohexanehexol derivatives. More specifically, the invention provides a medicament comprising cyclohexanehexol derivatives of formula III or formula IV, more particularly a scyllo-inositol compound, analog or derivative thereof, useful in the treatment of polyglutamine diseases, such as Huntington' s disease and related neurodegenerative disorders including dentatorubral pallidoluysian atrophy, spinal and bulbar muscular atrophy and spinocerebellar ataxia type 1, 2, 3, 6, 7 and 17. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5765839-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859628-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833420-B2 |
| priorityDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1088.