http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008124929-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b628ab81e049bcc77a733f92cb051c2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-047 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate | 2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd38b7007d8437dbc1e38a6c029b7b49 |
publicationDate | 2008-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2008124929-A1 |
titleOfInvention | USE OF CYCLOHEXANEHEXOL DERIVATIVES IN THE TREATMENT OF α-SYNUCLEINOPATHIES |
abstract | The present invention relates to methods for treating α-synucleinopathies, methods for modulating of assembly, folding, accumulation, oligomerization, rate of aggregation, oligomerization and clearance of proteins of fragments comprising α-synuclein aggregates in a subject, by administering a medicament comprising a therapeutically effective amount of a cyclohexanehexol derivative. More specifically, the invention provides medicaments comprising at least one cyclohexanehexol derivative of formula (III) or (IV) useful in improving neuron, glia and oligodendrocyte function, for slowing the degeneration and death of neurons, glial cells and oligodendrocytes in the brain and treating synucleinopathies such as Parkinson's disease. These medicaments are formulated for oral and parenteral administration. Formulae (III), (IV). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859628-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833420-B2 |
priorityDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 838.