| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4737df8e757c44eef7d18b404349b2ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f5c4dd6dab9b54c1b2689ae968fcdce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17264573c80e732926ec18d6c9517048 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N25-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N25-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N41-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2008-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a91303daab9c84dcc3663a385e3a82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad1142312ea3b2d3600ad2b46983b558 |
| publicationDate |
2008-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008120219-A2 |
| titleOfInvention |
Compositions and methods for cell killing |
| abstract |
The present invention discloses an insoluble proton sink or source (PSS), useful for killing living target cells (LTCs), or otherwise disrupting vital intracellular processes and/or intercellular interactions of the LTC upon contact. The PSS comprises (i) proton source or sink providing a buffering capacity; and (ii) means providing proton conductivity and/or electrical potential. The PSS is effectively disrupting the pH homeostasis and/or electrical balance within the confined volume of the LTC and/or disrupting vital intercellular interactions of the LTCs while efficiently preserving the pH of the LTCs' environment. The invention also provides articles of manufacture comprises the PSS and presents an effective method for killing the LTCs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011067762-A3 |
| priorityDate |
2007-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |