Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d96b9c5efb8d0fa8cb707b5096ced886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e092ba7c0b4f2beba27b6420c0bd2ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee4bffe97fa230b727fee361b06d9c65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36a05b930f82f24b1b97276f45caf156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b977d87fa07132796e3acc3cc325709f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-035 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2008-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bed1e73d329981556e77d8763824e507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd326317c3c0c3ddf1b2789949fff0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1776367b6ba68ddd3374e5e1c65ea03e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1727e31d7edaf4b33f5fd10ff1ea4b42 |
publicationDate |
2008-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008117199-A2 |
titleOfInvention |
Animal model, system, and method for screening compounds for antithrombotic and/or thrombolytic activity |
abstract |
The present invention relates to a method for evaluating a test compound for antithrombotic activity, thrombolytic activity, or a combination thereof. This method can include providing or employing a donor test animal and a recipient test animal. The donor and recipient test animals can have been pretreated with test compound. The donor test animal can be configured to provide oxygenated blood to the recipient test animal through a thrombus inducing system. This method also includes initiating transport of blood from the donor test animal to the recipient test animal through the thrombus inducing system. The method can include interrupting respiration of the recipient test animal and determining the length of time that the recipient test animal survives. In this method, a survival time longer than a predetermined threshold time indicates that the test compound has antithrombotic activity, thrombolytic activity, or a combination thereof. |
priorityDate |
2007-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |