| abstract |
The present invention relates to a CB1 antagonist and a dyslipidemic agent and/or a metabolic regulator. The present invention further includes methods of using formulations of a CB1 antagonist and at least one of (a) omega-3 fatty acids, (b) MTP inhibitors, (c) DPP4 inhibitors, (d) sarsasapogenin, (e) smilagenin, (f) steroidal glycosides and/or (g) extracts of Artemisia spp. for treating various dyslipidemias; treating vascular disease; treating artherosclerotic disease; treating obesity; preventing or reducing cardiovascular and vascular events; reducing insulin resistance, fasting glucose levels and postprandial glucose levels; treating and/or preventing diabetes and/or symptoms thereof; reducing the incidence of and/or delaying the onset of metabolic syndrome; and reducing the incidence of, and/or delay the onset of type II diabetes. |