| abstract |
The present invention relates to peptides comprising a fragment of the human alpha- fetoprotein molecule of SEQ ID NO: 1, wherein said peptides comprise: (a) amino acids 46-55 of SEQ ID NO: 1; (b) a variant of (a) in which one, two or three amino acids are deleted; or (c) a variant of (a) comprising one, two, three or four amino acid substitutions from the sequence of (a); wherein said peptide is capable of activating T cells that produce TGF-β and/or GM-CSF, and wherein said peptide does not comprise a B cell epitope, a CTL epitope or a ThI epitope. |