| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_822e07dcda0fd00f7a895e21546cda7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d50a5d08fff80f620aa6f328cd9bc85e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd9a68b75c269550a54a286020170d1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5c852288d9dae2a8189dee8d789b9bf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-703 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate |
2008-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0453c77fc8ad45b67a958c2fc345415a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9704c9e9e6fb2a6345b797bbbd15dfd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f618e00da3d9b7ea9ae6e2f63170dbe |
| publicationDate |
2008-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008109785-A2 |
| titleOfInvention |
Hiv reverse transcriptase compositions and methods |
| abstract |
The present invention provides engineered novel variants of human immunodeficiency virus reverse transcriptase (HIV-RT) capable of being expressed in large quantity and that with polymerase and RNase H activity in a form that facilitates crystallization and high resolution structure resolution following X-ray diffraction. The present invention facilitates high resolution determination of RT in complexes with RT drugs and RT inhibitors, and provides methods for systematic generation of variants and for structure based identification and design of novel RT inhibitors. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011073959-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8754093-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-024299-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010112411-A1 |
| priorityDate |
2007-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |