abstract |
The present invention relates to Pyrimxdo [5,4-c]quinoline-2, 4 -diamine Derivatives, compositions comprising an effective amount of a Pyrimido [5, 4 -c] quinoline-2, 4 -diamine Derivative of formula (I), methods for treating or preventing a proliferative disorder, comprising administering to a subject in need thereof an effective amount of an Pyrimido [ 5, 4 - c] quinoline-2, 4 -diamine Derivative. Disclosed are also methods for modulating PDK-I activity, comprising administering to a subject in need thereof an effective amount of a Pyrimido [5,4- c] quinoline- 2,4-diamine Derivative. The invention also relates to a process for preparing a Pyrimido [5,4- c] quinoline-2, 4 -diamine Derivative or a pharmaceutically acceptable salt thereof, |