| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0db8f8ba5107d9d953fa5c616fdfc65e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a551cabbb1cdd0bbfe4b0bf1908781d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c50a38897767b90b3f9e84925e7f9b69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3cbd9eb240385f433ae8a368189eed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4471cb5e5f3841893dcd446776544111 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-48 |
| filingDate |
2008-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edb3b627e360c1ea50986a127754c323
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ffd95fce12afb53286460fdef1467a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87a7ff7387c9f968c8e1c43150d76280
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57e324d2abb96194cf5a7b02ce8e3fe4 |
| publicationDate |
2008-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008107482-A1 |
| titleOfInvention |
Scaffolds for the regeneration of cartilage |
| abstract |
The present application discloses that incorporation of dermatan sulfate and/or HA in composite scaffolds of certain polymers gives rise to a chondrogenic effect on chondrocytes resulting in formation of cartilage that resembles the natural ECM. This effect with dermatan sulfate as the primary additive has not previously been seen. The composites are formed by incorporation of dermatan sulfate finely dispersed particles optionally nanoparticles or as molecular dissolutions in a polymer matrix with no bonding between the DS and the matrix, providing the DS to the chondrocytes in an accessible non-crosslinked form. |
| priorityDate |
2007-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |