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publicationDate 2008-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008105486-A1
titleOfInvention Reagent for determination of quantity of small dense low-density lipoprotein
abstract Disclosed is a reagent for the fractional determination of a small dense LDL, which does not need any pretreatment of a sample, is rapid and simple, and is applicable to an automated analyzer. Also disclosed is a method for the determination of the quantity of cholesterol contained in a small dense low-density lipoprotein in a sample, which comprises: a first step for scavenging a lipoprotein other than the small dense low-density lipoprotein in the sample in the presence of cholesterol esterase and a surfactant capable of acting on a lipoprotein other than the small dense low-density lipoprotein at a concentration of 0.05 to 1.0 g/L; and a second step for determining the quantity of cholesterol in the small dense low-density lipoprotein remaining in the first step.
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